| # | Date | Promotion | Match |
| 1 | 07.02.2017 |  |
John Cena defeats Randy Orton (12:00) WWE SmackDown Live #912 - TV-Show @ KeyArena in Seattle, Washington, USA |
| 2 | 26.10.2014 |  |
WWE World Heavyweight Title #1 Contendership Hell In A Cell: John Cena defeats Randy Orton (26:25) WWE Hell In A Cell 2014 - Premium Live Event @ American Airlines Center in Dallas, Texas, USA |
| 3 | 22.09.2014 |  |
John Cena defeats Randy Orton by DQ (15:15) WWE Monday Night RAW #1113 - TV-Show @ FedExForum in Memphis, Tennessee, USA |
| 4 | 10.02.2014 | |
John Cena defeats Randy Orton (20:42) WWE Monday Night RAW #1081 - TV-Show @ Staples Center in Los Angeles, California, USA |
| 5 | 26.01.2014 |  |
WWE World Heavyweight Title: Randy Orton (c) defeats John Cena (20:54) WWE Royal Rumble 2014 - Pay Per View @ CONSOL Energy Center in Pittsburgh, Pennsylvania, USA |
| 6 | 15.12.2013 | |
WWE Heavyweight Title / World Heavyweight Title Unification Tables, Ladders & Chairs: Randy Orton (c) [WWE] defeats John Cena (c) [World] (24:35) - TITLE CHANGE !!! WWE TLC: Tables, Ladders & Chairs 2013 - Pay Per View @ Toyota Center in Houston, Texas, USA |
| 7 | 25.10.2010 |  |
John Cena defeats Randy Orton by DQ (15:38) WWE Monday Night RAW #909 - TV-Show @ Resch Center in Green Bay, Wisconsin, USA |
| 8 | 13.09.2010 | |
Tables: Randy Orton defeats John Cena (16:50) WWE Monday Night RAW #903 - TV-Show @ US Bank Arena in Cincinnati, Ohio, USA |
| 9 | 14.12.2009 | |
Superstar Of The Year 2009 Tournament Final: John Cena defeats Randy Orton (9:01) WWE Monday Night RAW #864 - TV-Show @ American Bank Center in Corpus Christi, Texas, USA |
| 10 | 25.10.2009 | |
WWE Heavyweight Title Anything Goes 60 Minute Iron Man: John Cena defeats Randy Orton (c) [6:5] (60:00) - TITLE CHANGE !!! WWE Bragging Rights 2009 - Pay Per View @ Mellon Arena in Pittsburgh, Pennsylvania, USA |
| 11 | 04.10.2009 | |
WWE Heavyweight Title Hell In A Cell: Randy Orton defeats John Cena (c) (21:24) - TITLE CHANGE !!! WWE Hell In A Cell 2009 - Pay Per View @ Prudential Center in Newark, New Jersey, USA |
| 12 | 13.09.2009 | |
WWE Heavyweight Title I Quit: John Cena defeats Randy Orton (c) (19:48) - TITLE CHANGE !!! WWE Breaking Point - Pay Per View @ Bell Centre in Montreal, Quebec, Canada |
| 13 | 23.08.2009 | |
WWE Heavyweight Title: Randy Orton (c) defeats John Cena (20:45) WWE SummerSlam 2009 - Pay Per View @ Staples Center in Los Angeles, California, USA |
| 14 | 12.05.2008 | |
Match (Special Referee: John Bradshaw Layfield): Randy Orton defeats John Cena (9:30) WWE Monday Night RAW #781 - TV-Show @ Joe Louis Arena in Detroit, Michigan, USA |
| 15 | 18.02.2008 | |
Match (Special Referee: Triple H): John Cena defeats Randy Orton (11:20) WWE Monday Night RAW #769 - TV-Show @ Arrowhead Pond in Anaheim, California, USA |
| 16 | 17.02.2008 | |
WWE Heavyweight Title: John Cena defeats Randy Orton (c) by DQ (15:56) WWE No Way Out 2008 - Pay Per View @ Thomas & Mack Center in Las Vegas, Nevada, USA |
| 17 | 16.09.2007 | |
WWE Heavyweight Title: Randy Orton defeats John Cena (c) by DQ (7:33) WWE Unforgiven 2007 - Pay Per View @ FedExForum in Memphis, Tennessee, USA |
| 18 | 26.08.2007 | |
WWE Heavyweight Title: John Cena (c) defeats Randy Orton (21:18) WWE SummerSlam 2007 - Pay Per View @ Izod Center in East Rutherford, New Jersey, USA |
| 19 | 19.02.2007 | |
John Cena defeats Randy Orton by DQ (13:04) WWE Monday Night RAW #717 - TV-Show @ Rabobank Arena in Bakersfield, California, USA |
| 20 | 13.11.2005 |  |
John Cena defeats Randy Orton by DQ (3:38) WWE Monday Night RAW #651 - Eddie Guerrero Tribute - TV-Show @ Target Center in Minneapolis, Minnesota, USA |
| 21 | 16.01.2002 |  |
Prototype defeats Randy Orton OVW TV - TV-Show @ Davis Arena in Louisville, Kentucky, USA |
| 22 | 09.08.2001 |  |
Randy Orton defeats Prototype 4th Annual Brian Pillman Memorial Show - Event @ Oak Hills High School in Oak Hills, Ohio, USA |
