| # | Date | Promotion | Match |
| 1 | 08.01.2006 |  |
WWE Heavyweight Title: Edge defeats John Cena (c) (1:41) - TITLE CHANGE !!! WWE New Year's Revolution 2006 - Pay Per View @ Pepsi Center in Albany, New York, USA |
| 2 | 08.01.2006 | |
WWE Heavyweight Title Elimination Chamber: John Cena (c) defeats Carlito and Chris Masters and Kane and Kurt Angle and Shawn Michaels (28:24) WWE New Year's Revolution 2006 - Pay Per View @ Pepsi Center in Albany, New York, USA |
| 3 | 28.11.2005 |  |
WWE Heavyweight Title No Holds Barred Submission Triple Threat: John Cena (c) defeats Chris Masters and Kurt Angle (7:01) WWE Monday Night RAW #653 - TV-Show @ Quicken Loans Arena in Cleveland, Ohio, USA |
| 4 | 27.11.2005 | |
WWE Heavyweight Title Match (Special Referee: Daivari): John Cena (c) defeats Kurt Angle (13:50) WWE Survivor Series 2005 - Pay Per View @ Joe Louis Arena in Detroit, Michigan, USA |
| 5 | 01.11.2005 | |
WWE Heavyweight Title Triple Threat: John Cena (c) defeats Kurt Angle and Shawn Michaels (16:45) WWE Taboo Tuesday 2005 - Pay Per View @ ipayOne Center in San Diego, California, USA |
| 6 | 03.10.2005 | |
WWE Heavyweight Title No Disqualification: John Cena (c) defeats Eric Bischoff (2:44) WWE Monday Night RAW #645 - WWE Homecoming - TV-Show @ American Airlines Arena in Dallas, Texas, USA |
| 7 | 18.09.2005 | |
WWE Heavyweight Title: Kurt Angle defeats John Cena (c) by DQ (17:13) WWE Unforgiven 2005 - Pay Per View @ Ford Center in Oklahoma City, Oklahoma, USA |
| 8 | 22.08.2005 |  |
WWE Heavyweight Title Loser Leaves Town: John Cena (c) defeats Chris Jericho (15:30) WWE RAW #639 - TV-Show @ Hampton Coliseum in Hampton, Virginia, USA |
| 9 | 21.08.2005 | |
WWE Heavyweight Title: John Cena (c) defeats Chris Jericho (14:51) WWE SummerSlam 2005 - Pay Per View @ MCI Center in Washington, District Of Columbia, USA |
| 10 | 01.08.2005 | |
WWE Heavyweight Title Match (Special Referee: Chris Jericho): John Cena (c) defeats Carlito (12:12) WWE RAW #636 - TV-Show @ Mohegan Sun Arena in Uncasville, Connecticut, USA |
| 11 | 26.06.2005 | |
WWE Heavyweight Title Triple Threat: John Cena (c) defeats Chris Jericho and Christian (15:19) WWE Vengeance 2005 - Pay Per View @ Thomas & Mack Center in Las Vegas, Nevada, USA |
| 12 | 20.06.2005 | |
WWE Heavyweight Title: John Cena (c) defeats Muhammad Hassan (2:19) WWE RAW #630 - TV-Show @ America West Arena in Phoenix, Arizona, USA |
| 13 | 22.05.2005 | |
WWE Heavyweight Title I Quit: John Cena (c) defeats John Bradshaw Layfield (22:40) WWE Judgment Day 2005 - Pay Per View @ Target Center in Minneapolis, Minnesota, USA |
| 14 | 03.04.2005 | |
WWE Heavyweight Title: John Cena defeats John Bradshaw Layfield (c) (11:18) - TITLE CHANGE !!! WWE WrestleMania 21 - "WrestleMania Goes Hollywood" - Pay Per View @ Staples Center in Los Angeles, California, USA |
