| # | Date | Promotion | Match |
| 1 | 11.06.2006 |  |
WWE Heavyweight Title: Rob Van Dam defeats John Cena (c) (20:45) - TITLE CHANGE !!! ECW One Night Stand 2006 - Pay Per View @ Hammerstein Ballroom in New York City, New York, USA |
| 2 | 15.05.2006 |  |
WWE Heavyweight Title / Intercontinental Title Texas Tornado Three On Two Handicap: Chris Masters, Shelton Benjamin & Triple H defeat John Cena (c) [WWE] & Rob Van Dam (c) [Intercontinental] (12:57) - TITLE CHANGE !!! WWE Monday Night RAW #677 - TV-Show @ Texas Tech University in Lubbock, Texas, USA |
| 3 | 01.05.2006 | |
WWE Heavyweight Title Match (Special Referee: Triple H): John Cena (c) defeats Kenny (8:02) WWE Monday Night RAW #675 - TV-Show @ Nationwide Arena in Columbus, Ohio, USA |
| 4 | 30.04.2006 |  |
WWE Heavyweight Title No Disqualification Triple Threat: John Cena (c) defeats Edge and Triple H (17:34) WWE Backlash 2006 - Pay Per View @ Rupp Arena in Lexington, Kentucky, USA |
| 5 | 02.04.2006 | |
WWE Heavyweight Title: John Cena (c) defeats Triple H (22:11) WWE WrestleMania 22 - "Big Time" - Pay Per View @ Allstate Arena in Rosemont, Illinois, USA |
| 6 | 13.02.2006 | |
WWE Heavyweight Title Match (Special Referee: Mick Foley): John Cena (c) defeats Edge (19:45) WWE Monday Night RAW #664 - Thursday Night RAW - TV-Show @ Greensboro Coliseum in Greensboro, North Carolina, USA |
| 7 | 30.01.2006 | |
WWE Heavyweight Title: Edge defeats John Cena (c) by DQ (11:40) WWE Monday Night RAW #662 - TV-Show @ TD Waterhouse Center in Orlando, Florida, USA |
| 8 | 29.01.2006 | |
WWE Heavyweight Title: John Cena defeats Edge (c) (14:02) - TITLE CHANGE !!! WWE Royal Rumble 2006 - Pay Per View @ AmericanAirlines Arena in Miami, Florida, USA |
